The pyrogen tests are performed for teh purpose of determining the prognosis of any reactions that might develop in the patient administered by parenteral solutions via injection.
The rabbit is used in the assays.
   
The assays are performed by observing thedevelopment of fever in the subject animals via injection parenteral solutions of 10 mL for 1 kg into the ear venal.
Since 2001, the pyrogen tests are conducted in Polifarma Pharmaceutical by Ellab Pyromon testing device automatically in conformity with high technology international pharmacopeias.

Polifarma Pharmaceutical is the sole serum manufacturer conducting pyrogen tests in parenteral production and control processes.